Wondering where to find out product information such as active ingredients or scientific studies in anti-aging products? Look no further, you're in the right place.
Tuesday, 16 February 2016
Skin protection with Glissandra. Protect against damaging rays.
Glissandra's proprietary ingredient Glissandrin helps to ward off the effects of UV and infrared damaging rays also known as solar-irradiation which induces oxidative injury to skin tissues and skin cells.
Glissandra makes UV protection simple and effective with their skincare and supplement product line.
Rain or Shine, Glissandra products are there to minimize the damaging effects of the sun.
Glissandra™ Skincare Inc. 305-5811 Cooney Road Richmond, BC Canada, V6X3M1
- Tel: 1-877-313-7242
- Fax: 604-433-7527
- Email: info@glissandra.com
Glissandrin versus Schisandrin by Glissandra Inc.
What is the differance between Glissandrin and
Schisandrin?
Schisandrin is the chemistry located within the Schissandra Berry which is harvested from the North East part of China and used in Glissandra's products. Schissandrin's are known to contain anit-aging properties and have been utilized in TCM (traditional Chinese Medicine) for centuries. Considered a herb, the schissandra berry has been extensively studied, researched and documented in scientific journals.
Glissandrin, is Glissandra's propreitary ingredient consisting of a suite of Schisandrins such as vitamins A, B, C and -B. A labour of love, Glissandrin has been formulated to deal with the root cause of aging (mitochondria) and change cellular reactions to anti-oxidants (free radicals).
Glissandra's products deal with the root cause of aging rather than masking the effects.
Glissandra™ Skincare Inc. 305-5811 Cooney Road Richmond, BC Canada, V6X3M1
- Tel: 1-877-313-7242
- Fax: 604-433-7527
- Email: info@glissandra.com
Tuesday, 2 February 2016
UNCOUPLING FACTOR/PROTEINS
WHAT ARE UNCOUPLING PROTEINS?
Uncoupling proteins are transporters, present in the
mitochondrial inner membranes that utilize the spread of protons (positive electoral
atoms) to reduce the amount of oxidant damage generated through ATP production
(transport of energy for metabolism). Energy
production is used to generate heat instead of producing energy for metabolism
of cells.[i]
The hypothesis that uncoupling proteins of the mitochondrial membrane can
reduce body adiposity (fat) and that lower metabolic weight gain.[ii]
Note: There are 5 different types of uncoupling proteins
each with their own functions and chemistry.[iii]
The subject of uncoupling proteins is scientifically advanced. The above statement is a shortened version of the
extensive science behind the process. To research uncoupling proteins please refer to scientific journals as your source.
Alzheimers, Huntington's, ALS and Parkinson's Neurodegenerative Diseases
Can brain degeneration be combatted?
Neurodegenerative
Diseases
Brain
Degenerative Diseases such as Huntington’s, Parkinson’s, Amyotrophic Lateral Sclerosis
(ALS) and all forms of dementia including Alzheimer’s are all classified as
diseases affected by brain. Degenerative brain diseases have an enormous impact
on our aging society. Alzheimer's disease progressively robs its victims of
their memory. Parkinson's disease leads to impairments in movement.
Frontotemporal (occurring the front area of the brain) dementia causes
bewildering changes in a person's thoughts and behaviour. Huntington's disease
painstakingly deprives a person of their ability to walk, talk, think and
reason, often as early as in their mid-30s and 40s. In all of these
degenerative brain diseases, the time from the onset of symptoms until death
can be as many as ten or twenty years, with many sufferers' lives characterised
by a total loss of independence in their final years.[i]
Over
production of ROS (oxidative stress) is a central feature of all
neurodegenerative disorders.[ii]
There is strong evidence that mitochondrial
dysfunction and oxidative
stress plays a role in
neurodegenerative disease pathogenesis, including four of the more well-known diseases
Alzheimer's, Parkinson's, Huntington's, and Amyotrophic lateral sclerosis
(ALS).[iii]
Alzheimer's Disease
Alzheimer's disease is characterised
by loss of neurons (specialized nerve cells) and synapses (nerve cell
signaling) in the cerebral cortex (outer layer of frontal part of the brain playing a role in
consciousness) and certain subcortical regions (functional, connective and
developmental areas of the brain). This loss results in gross atrophy
(shrinkage) of affected areas of the brain.
Parkinson's Disease
Parkinson's
disease is the second most common neurodegenerative disorder. Parkinson's
disease is a degenerative disorder of the central nervous system. It
results from the death of dopamine-generating (neuro-transmitter that send
signals to other nerve cells).
Huntington's Disease
Huntington’s
Disease causes astrogliosis (decrease of brain and spinal cord cells) and loss of
neurons (specialized nerve cells). Areas
of the brain are affected according to their structure and the types of neurons
they contain, reducing in size as they cumulatively lose cells.
Amyotrophic Lateral Sclerosis (ALS) also commonly known as Lou Gehrig’s Disease
Amyotrophic
lateral sclerosis (ALS or Lou Gehrig’s Disease) is a disease in which motor
neurons are selectively targeted for degeneration affecting movement and speech.
Aging and Neurodegeneration
The greatest
risk factor for neurodegenerative diseases is aging. Mitochondrial DNA
mutations as well as oxidative stress both contribute to aging. Many of these diseases are late-onset, meaning
there is some factors that change as a person ages for each disease. One
constant factor is that in each disease, neurons (specialized nerve cells)
gradually lose function as the disease progresses with age.[iv]
Cell health is imperative to mitigate
the damaging effects associated with degenerative disease.
Tuesday, 26 January 2016
Schisandrin B can help with damaging effects of UV exposure.
Exposure to UV (ultraviolet) radiation can have an impact on health.
Sunlight is the major cause of UV exposure. Although sunlight has some benefits to the
body such as the absorption of vitamin D and aiding in the treatment of specific
medical procedures, care must be taken to avoid unnecessary exposure.
Free radicals (such as short wave UV radiation from the sun) alter the structure of the body’s cells eventually leading to cell death. Risks associated with overexposure to UV light are erythema (redness and inflammation) premature aging, eye damage, skin cancer/s and weakening of the immune system.
“Excessive exposure to ultraviolet radiation is associated
with different types of skin cancer, sunburn, accelerated skin aging, as well
as cataracts and other eye diseases. The severity of the effect depends on the
wavelength intensity and duration of exposure”[1]
Schisandrin B can be a protective barrier to UV
exposure. Schisandrin
B, a key component of Glissandrin™, can protect against solar irradiation-induced
oxidative injury in skin tissue and skin cells, according to recent research
findings from the laboratory of Dr. Robert Ko at the Hong Kong University of
Science and Technology.[2]
As the largest organ in the human body, the skin
serves as an effective barrier for protecting against various external threats.
This includes exposure to harmful solar irradiation – particularly UV and
infrared rays-which research has shown to be a major cause of skin aging. Although
human skin tissue possesses non-enzymatic and enzymatic antioxidant defense
systems (built in anti-oxidant eradication processes) to cope with the
increased oxidative stress caused by solar light radiation, long-term exposure
or overexposure to solar light can overwhelm the antioxidant system.[3] When the
antioxidant system is taxed, cell death occurs which leads to aging.
What if there was a way to enhance the skin’s
natural antioxidant defenses to prevent photo-aging entirely? Schisandrin B
(Sch B) is able to do just that, ushering in a new era in UV protective
skincare. Schisandrin B is derived from the Schisandra fruit, an herb commonly
used in Traditional Chinese Medicine (TCM). This naturally occurring herbal
ingredient has been found to produce tissue non-specific protection against
oxidative injury by enhancing cellular and mitochondrial glutathione
antioxidant status in the heart, liver, kidney, and brain.[4]
The countries with
the highest rates of skin cancers may surprise you.
The top three countries
with the highest rates of skin cancer and ranked per death/100,000 people are
New Zealand, Australia and Slovenia. Often, these individuals also are
diagnosed with melanoma which is the most virulent form of skin cancer. Kiwi's
(New Zealander's) and Aussie's (Australians) are sun loving nations with
residents being approximately 13 more times likely to develop skin carcinomas.
The KEY in preventing skin damage is to take
precautions such as limiting over excessive sun exposure, covering up when
required and the constant application of UV protection products. Another way to protect the skin from UV damage
is to provide a protective barrier using Shisandrin B based products.
More
information on Schisandrin B can be found at these independent websites:
•
National Institutes of Health (http://www.nih.gov/)
•
PubMed (http://www.ncbi.nlm.nih.gov/pubmed/)
•
Natural Medicines https://naturalmedicines.therapeuticresearch.com
(formerly National Standards)
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